Description
IL-23 Antibody (Center Region) | F53999-0.2ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse
Application: WB
Buffer: N/A
Limitation: This IL-23 antibody is available for research use only.
Purity: Antigen affinity
Description: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen: Amino acids 33-67 from the human protein were used as the immunogen for this IL-23 antibody.
Storage: Aliquot the IL-23 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
