IL-2 Receptor Antibody beta 2 subunit / IL2RB2 | F54552-0.08ML

IL-2 Receptor Antibody beta 2 subunit / IL2RB2 | F54552-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P, WB, FACS

Buffer: N/A

Limitation: This IL12RB2 antibody is available for research use only.

Purity: Antigen affinity purified

Description: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.

Immunogen: A portion of amino acids 756-783 from the human protein was used as the immunogen for the IL12RB2 antibody.

Storage: Aliquot the IL12RB2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.