Description
IL-10 Antibody | F51527-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, FACS, ELISA
Buffer: N/A
Limitation: This IL-10 antibody is available for research use only.
Purity: Antigen affinity
Description: The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Immunogen: A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.
Storage: Aliquot the IL-10 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
