IL-10 Antibody | F51527-0.08ML

IL-10 Antibody | F51527-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, FACS, ELISA

Buffer: N/A

Limitation: This IL-10 antibody is available for research use only.

Purity: Antigen affinity

Description: The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

Immunogen: A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.

Storage: Aliquot the IL-10 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.