Description
IKKβ Kinase Assay Kit | 78507 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Assay Kit
Application: Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.
Background: The IKKβ (inhibitor of nuclear factor kappa B kinase subunit beta) is a protein subunit encoded by the IKβKβ (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene which activates NF-κB (nuclear factor kappa-light chain enhancer of activated B cells) signaling. NF-κB is a family of transcription factors that regulate gene expression in a variety of tissue types. Mutations in IKKB result in defective NF-κB signaling leading to immunological disorders. Exploring novel mutations in IKKB may elucidate the causation of sporadic and unexplained diseases.
Description: The IKKβ Kinase Assay Kit is designed to measure the kinase activity of IKKβ for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
Product Type: Assay Kit
Shippement Condition: -80°C
