Description
IKK alpha/beta Antibody | RQ4722 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: FCC-3
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This IKK alpha/beta antibody is available for research use only.
Purity: Affinity purified
Description: The IkappaB kinase complex is composed of three subunits each encoded by a separate gene: IKK alpha (also known as IKK1 and CHUK), IKK beta (also known as IKK2 and IKBKB), and IKK gamma (also known as NEMO/ and IKBKG). The alpha- and beta- subunits together are catalytically active whereas the gamma-subunit serves a regulatory function. The IKKa and IKKb kinase subunits are homologous in structure, composed of a kinase domain, as well as leucine zipper and helix-loop-helix dimerization domains, and a carboxy-terminal NEMO-binding domain (NBD). [Wiki]
Immunogen: A synthetic peptide amino acid sequence specifc for and common to human IKK alpha and beta was used as the immunogen for the IKK alpha/beta antibody.
Storage: Store the IKK alpha/beta antibody at -20 °C.
