Description
IkBa Antibody | F52272-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide
Format: Purified
Clone: 1121CT8.6.1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This IkBa antibody is available for research use only.
Purity: Purified
Description: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Immunogen: Purified His-tagged protein was used to produced this monoclonal IkB alpha antibody.
Storage: Aliquot the IkBa antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
