IkBa Antibody | F52272-0.08ML

IkBa Antibody | F52272-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: 1121CT8.6.1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This IkBa antibody is available for research use only.

Purity: Purified

Description: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Immunogen: Purified His-tagged protein was used to produced this monoclonal IkB alpha antibody.

Storage: Aliquot the IkBa antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.