IKAROS Antibody / IKZF1 | F54538-0.4ML

IKAROS Antibody / IKZF1 | F54538-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, IHC-P

Buffer: N/A

Limitation: This IKAROS antibody is available for research use only.

Purity: Antigen affinity purified

Description: Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). [UniProt]

Immunogen: A portion of amino acids 415-444 from the human protein was used as the immunogen for the IKAROS antibody.

Storage: Aliquot the IKAROS antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.