IGF2R Antibody / M6PR | F53870-0.05ML

IGF2R Antibody / M6PR | F53870-0.05ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This IGF2R antibody is available for research use only.

Purity: Antigen affinity

Description: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

Immunogen: A portion of amino acids 2424-2458 from the human protein was used as the immunogen for the IGF2R antibody.

Storage: Aliquot the IGF2R antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.