IGF1R Antibody / Insulin like growth factor 1 receptor | F54940-0.4ML

IGF1R Antibody / Insulin like growth factor 1 receptor | F54940-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: IHC-P, WB

Buffer: N/A

Limitation: This IGF1 Receptor antibody is available for research use only.

Purity: Purified

Description: The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.

Immunogen: A portion of amino acids 1335-1366 from the human protein was used as the immunogen for the IGF1 Receptor antibody.

Storage: Aliquot the IGF1 Receptor antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.