Description
IGF1R Antibody / Insulin like growth factor 1 receptor | F54940-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: IHC-P, WB
Buffer: N/A
Limitation: This IGF1 Receptor antibody is available for research use only.
Purity: Purified
Description: The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Immunogen: A portion of amino acids 1335-1366 from the human protein was used as the immunogen for the IGF1 Receptor antibody.
Storage: Aliquot the IGF1 Receptor antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.