Description
IGF1 Receptor Antibody (IGF1R) | F50633-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This IGF1R antibody is available for research use only.
Purity: Purified
Description: The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Immunogen: A portion of amino acids 19-51 from the human protein was used as the immunogen for this IGF1R antibody.
Storage: Aliquot the IGF1R antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
