Description
IFNAR1 Polyclonal Antibody | E-AB-40306 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: IHC
Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Background: IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways are Type I Interferon Signaling Pathways and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include interferon receptor activity and type I interferon receptor activity. An important paralog of this gene is ENSG00000249624.The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Lead Time: 7~10 days
Concentration: 0.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Interferon alpha/beta receptor 1 protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification: Antigen Affinity Purification
Dilution: IHC 1:100-1:300
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: Polyclonal
