IDH1 Antibody / Isocitrate Dehydrogenase (R132H mutant) | V4026SAF-100UG

IDH1 Antibody / Isocitrate Dehydrogenase (R132H mutant) | V4026SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: IDH1/7277R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the Isocitrate Dehydrogenase R132H Mutant antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: IDH1 R132H antibody binds to IDH1-mutated protein, but does not bind the wild-type IDH1 protein. IDH1 R132H point mutations are frequently seen in World Health Organization grade II and III gliomas and are believed to constitute an early step in tumorigenesis.

Immunogen: A recombinant protein fragment specific the the IDH R132H Mutant was used as the immunogen for the Isocitrate Dehydrogenase R132H Mutant antibody.

Storage: Aliquot the Isocitrate Dehydrogenase R132H Mutant antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cytoplasm, nucleus