Description
IDH1 Antibody | F50422-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: IHC, IF, WB, FACS, ELISA
Buffer: N/A
Limitation: This IDH1 antibody is available for research use only.
Purity: Purified
Description: IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent Isocitrate Dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [Wiki]
Immunogen: A portion of amino acids 116-143 from the human protein was used as the immunogen for this IDH1 antibody.
Storage: Aliquot the IDH1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
