Description
ID1 Antibody / DNA binding protein inhibitor ID-1 | V8940SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: PCRP-ID1-2F11
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, FACS, IF
Buffer: N/A
Limitation: This ID1 antibody is available for research use only.
Purity: Protein A/G affinity
Description: Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1, Id2, Id3 and Id4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since Id1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression.
Immunogen: A portion of amino acids 5-150 was used as the immunogen for the ID1 antibody.
Storage: Aliquot the ID1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.