Description
ICOSL (B7-H2) -CHO Recombinant Cell Line | 79635 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Cell Line
Application: This cell line is useful for screening for ICOSL antibodies through flow cytometry, immunocytochemistry or Western blot.
Background: ICOSL is the Ligand for the T-cell-specific cell surface receptor ICOS. When engaged by the ICOSL, the ICOS initiates a costimulatory signal for T-cell proliferation and cytokine production. It also induces B-cell proliferation and differentiation into plasma cells. The ICOS/ICOSL is a major regulator of the adaptive immune responses and also plays an important role in mediating local tissue responses to inflammatory conditions.
Description: Recombinant CHO-K1 cells constitutively expressing human ICOSL (also known as human secreted B7 homolog 2 (B7-H2), CD275, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050.
Product Type: Cell Line
Shippement Condition: -80°C
