Description
ICOS-L Antibody / ICOS Ligand / B7RP-1 | V7532-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: ISLG-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P, IF, FACS
Buffer: N/A
Limitation: This ICOS Ligand antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). [UniProt]
Immunogen: A recombinant fragment of human ICOSLG / B7RP-1 protein within amino acids 23-149 was used as the immunogen for the ICOS Ligand antibody.
Storage: Store the ICOS Ligand antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).