ICAM1 Antibody / CD54 | V2605-100UG

ICAM1 Antibody / CD54 | V2605-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: F4-31C2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: Functional studies, FACS, IF

Buffer: N/A

Limitation: This ICAM1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM1 also binds to CD43 and to Plasmodium falciparum infected RBCs and may also be related to progression and metastasis of tumors.

Immunogen: Human umbilical cord vein endothelial cells (HUVEC) were used as the immunogen for the ICAM1 antibody.

Storage: Store the ICAM1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).