Description
ICAM-3 Antibody / CD50 | V7507-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: ICAM3/2873R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG, kappa
Species Reactivity: Human
Application: Blocking, IHC-P
Application Details: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (order BSA/sodium azide-free format),Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
Application Note: Optimal dilution of the recombinant ICAM3 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Purity: Protein A affinity chromatography
Description: Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
Immunogen: Full length recombinant human protein was used as the immunogen for the recombinant ICAM3 antibody.
Storage: Store the recombinant ICAM3 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
Localization: Membrane, cytoplasm
