Description
ICAM-1 Antibody | R31437 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This ICAM-1 antibody is available for research use only.
Purity: Antigen affinity
Description: Intercellular adhesion molecule-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). It is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.
Immunogen: Human partial recombinant protein (amino acids 28-480) was used as the immunogen for this ICAM-1 antibody.
Storage: The lyophilized ICAM-1 antibody can be stored at 4oC. After reconstitution, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
