IBA1 Antibody / AIF-1 | V3830SAF-100UG

IBA1 Antibody / AIF-1 | V3830SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: AIF1/1909

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This IBA1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: AIF1 (Allograft inflammatory factor 1), also called IBA1 (Ionized calcium-binding adapter molecule 1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1/IBA1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, it colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding the protein resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

Immunogen: A portion of amino acids 1-146 from the human protein was used as the immunogen for the IBA1 antibody.

Storage: Store the IBA1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).