Human ZNRF3 protein, His Tag (MALS verified) | ZN3-H52H3-1mg

Human ZNRF3 protein, His Tag (MALS verified) | ZN3-H52H3-1mg| Gentaur Distribution US, UK & Europe

The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

Source: Human ZNRF3, His Tag (ZN3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 56 - Met 219 (Accession # Q9ULT6-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Lys 56 - Met 219.

Conjugate: Unconjugated.

Molecular Weight: 19.7 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.7 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT