Human uPAR / PLAUR Protein, Fc Tag (MALS verified) | UPR-H5254-1mg

Human uPAR / PLAUR Protein, Fc Tag (MALS verified) | UPR-H5254-1mg| Gentaur Distribution US, UK & Europe

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Source: Human uPAR, Fc Tag (UPR-H5254) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Arg 303 (Accession # Q03405-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Leu 23 - Arg 303.

Conjugate: Unconjugated.

Molecular Weight: 57.8 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.8 kDa. The protein migrates as 65-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT