Description
Human TSLP (R127A, R130A) Protein, Mouse IgG2a Fc Tag | TSP-H5255-100ug| Gentaur Distribution US, UK & Europe
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
Source: Human TSLP (R127A, R130A) Protein, Mouse IgG2a Fc Tag (TSP-H5255) is expressed from human 293 cells (HEK293). It contains AA Tyr 29 - Gln 159 (Accession # Q969D9-1 (R127A, R130A) ).
Format: Powder.
Tag: C-mFc (mIgG2a).
Expression System: HEK293.
Expression Region: Tyr 29 - Gln 159.
Conjugate: Unconjugated.
Molecular Weight: 41.6 kDa.
Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 41.6 kDa. The protein migrates as 50-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
