Description
Human Transthyretin / Prealbumin Protein, His Tag | TTR-H5223-1mg| Gentaur Distribution US, UK & Europe
Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family. Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1% of TTR's T4 binding sites are occupied in blood. TTR misfolding and aggregation is known to be associated with the amyloid diseases.
Source: Human Transthyretin, His Tag (TTR-H5223) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Glu 147 (Accession # NP_000362).
Format: Powder.
Tag: C-8×His.
Expression System: HEK293.
Expression Region: Gly 21 - Glu 147.
Conjugate: Unconjugated.
Molecular Weight: 14.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.9 kDa. The protein migrates as 17 kDa and 33 kDa under reducing (R) condition (SDS-PAGE) due to the monomer and dimer respectively.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT