Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified) | TN2-H5253-1mg

Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified) | TN2-H5253-1mg| Gentaur Distribution US, UK & Europe

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.

Source: Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (TN2-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Asp 257 (Accession # P20333-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Leu 23 - Asp 257.

Conjugate: Unconjugated.

Molecular Weight: 51.6 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.6 kDa. The protein migrates as 66-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT