Description
Human TIM-1 / HAVCR1 Protein, His Tag (MALS verified) | KI1-H52H3-100ug| Gentaur Distribution US, UK & Europe
Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.
Source: Human TIM-1 / HAVCR1, His Tag (KI1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Gly 295 (Accession # Q96D42-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Ser 21 - Gly 295.
Conjugate: Unconjugated.
Molecular Weight: 31.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.5 kDa. The protein migrates as 60-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
