Human Tau-441 / 2N4R (P301S) Protein, His Tag (MALS verified) | TAU-H5145-1mg

Human Tau-441 / 2N4R (P301S) Protein, His Tag (MALS verified) | TAU-H5145-1mg| Gentaur Distribution US, UK & Europe

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Source: Human Tau-441 (P301S), His Tag (TAU-H5145) is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301S) ).

Format: Powder.

Tag: N-10×His.

Expression System: E. coli.

Expression Region: Met 1 - Leu 441.

Conjugate: Unconjugated.

Molecular Weight: 47.7 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 47.7 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE).

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT