Description
Human TACI / TNFRSF13B Protein, His Tag | TAI-H52H3-1mg| Gentaur Distribution US, UK & Europe
Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA) and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK) 1/2 activation in A549 cells.
Source: Human TACI, His Tag (TAI-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Thr 166 (Accession # O14836-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Ser 2 - Thr 166.
Conjugate: Unconjugated.
Molecular Weight: 20.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.5 kDa. The protein migrates as 19-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, 0.2 M Arginine, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
