Description
Human SLC7A11&SLC3A2 Full Length Heterodimer Protein (VLP) | SLS-H52P4-20ug| Gentaur Distribution US, UK & Europe
Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring specialised transport systems for its import into the cell. System xc- is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc- is frequently upregulated, making it an attractive target for anticancer therapies.
Source: Human SLC7A11&SLC3A2 Full Length Heterodimer Protein (VLP) (SLS-H52P4) is expressed from human 293 cells (HEK293). It contains AA Val 2 - Leu 501 (SLC7A11) & Glu 2- Ala 630 (SLC3A2) (Accession # Q9UPY5 (SLC7A11) & P08195 (SLC3A2) ).
Format: Liquid.
Tag: N/A.
Expression System: HEK293.
Expression Region: Val 2 - Leu 501 (SLC7A11) & Glu 2- Ala 630 (SLC3A2).
Conjugate: Unconjugated.
Molecular Weight: N/A.
Characteristics: This protein .
Purity: N/A.
Buffer: PBS, Arginine, pH7.4.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
