Description
Human SIRP beta / CD172b Protein, Fc Tag (MALS verified) | SIA-H5257-100ug| Gentaur Distribution US, UK & Europe
Signal-regulatory protein beta-1 (SIRP beta 1) also known as SIRPβ1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. SIRPβ1 is a transmembrane protein that has three Ig-like domains in its extracellular region and a short cytoplasmic tail. Human SIRPβ1 is expressed on monocytes and granulocytes but not on lymphocytes. SIRP beta 1 contains short cytoplasmic domains that lack cytoplasmic sequence motifs capable of recruiting SHP-2 and SHP-1. In addition, they contain a single basic lysine residue within the hydrophobic transmembrane domain.
Source: Human SIRP beta, Fc Tag (SIA-H5257) is expressed from human 293 cells (HEK293). It contains AA Glu 30 - Leu 371 (Accession # O00241-1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Glu 30 - Leu 371.
Conjugate: Unconjugated.
Molecular Weight: 63.7 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 63.7 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
