Description
Human Siglec-5 / CD170 Protein, Fc Tag | SI5-H5250-1mg| Gentaur Distribution US, UK & Europe
Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2, 3-linked and alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Source: Human Siglec-5, Fc Tag (SI5-H5250) is expressed from human 293 cells (HEK293). It contains AA Glu 17 - Thr 434 (Accession # AAH29896).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Glu 17 - Thr 434.
Conjugate: Unconjugated.
Molecular Weight: 73.0 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.0 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
