Description
Human Serpin E2 / PN1 Protein, His Tag | SE2-H5225-25ug| Gentaur Distribution US, UK & Europe
SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1 (PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.
Source: Human Serpin E2, His Tag (SE2-H5225) is expressed from human 293 cells (HEK293). It contains AA Ser 20 - Pro 397 (Accession # P07093-2).
Format: Powder.
Tag: C-7×His.
Expression System: HEK293.
Expression Region: Ser 20 - Pro 397.
Conjugate: Unconjugated.
Molecular Weight: 42.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.8 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 20 mM Sodium Acetate, 100 mM NaCl, pH6.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
