Human PROCR / EPCR / CD201 Protein, Fc Tag | PRR-H5254-100ug

Human PROCR / EPCR / CD201 Protein, Fc Tag | PRR-H5254-100ug| Gentaur Distribution US, UK & Europe

Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.

Source: Human PROCR, Fc Tag (PRR-H5254) is expressed from human 293 cells (HEK293). It contains AA Ser 18 - Thr 209 (Accession # AAH14451).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Ser 18 - Thr 209.

Conjugate: Unconjugated.

Molecular Weight: 48.6 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT