Description
Human pIgR Protein, His Tag | PIR-H5222-100ug| Gentaur Distribution US, UK & Europe
Polymeric immunoglobulin receptor (PIGR) is also known as Poly-Ig receptor, which can be cleaved into membrane secretory component (SC). PIGR is a type I transmembrane glycoprotein or a member of the immunoglobulin superfamily, and is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Source: Human pIgR, His Tag (PIR-H5222) is expressed from human 293 cells (HEK293). It contains AA Lys 19 - Arg 638 (Accession # AAI10495.1).
Format: Powder.
Tag: C-6×His.
Expression System: HEK293.
Expression Region: Lys 19 - Arg 638.
Conjugate: Unconjugated.
Molecular Weight: 68.7 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 68.7 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT