Description
Human Parathyroid Hormone | 90231-B | Gentaur US, UK & Europe Disrtribition
Category: Cytokine
Application: N/A
Background: Parathyroid hormone is a circulating hormone that acts as the central regulator of calcium metabolism by directly targeting bone, kidney, and intestine. The classical concept of PTH action is that it regulates serum calcium levels by stimulating bone resorption, however, intermittent administration of PTH selectively stimulates bone formation. It is now known that PTH binds to its receptor PTH1R, and activates the G protein α subunits.Besides PKA and PKC activation, PTH also regulates MAPKs including p42/p44 ERKs, p38, and c-Jun N-terminal kinase subtypes.
Description: Recombinant Human PTH-84 is a disulfide-linked homodimeric protein consisting of 84 amino acid residues, and migrates as an approximately 9 kDa under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human PTH mature chain was expressed in E. coli.
Product Type: Protein
Shippement Condition: gel packs or dry ice
