Description
Human NKp46 / NCR1 / CD335 Protein, Fc Tag, premium grade | NC1-H5257-50ug| Gentaur Distribution US, UK & Europe
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Source: Human NKp46, Fc Tag (NC1-H5257) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asn 254 (Accession # AAH64806).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Gln 22 - Asn 254.
Conjugate: Unconjugated.
Molecular Weight: 53.0 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.0 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 10 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT