Description
Human NGFR / TNFRSF16 Protein, Fc Tag (MALS verified) | NGR-H5254-1mg| Gentaur Distribution US, UK & Europe
The p75 neurotrophin receptor (p75NTR) was originally identified as a low-affinity receptor for neurotrophins (NGF R).p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.
Source: Human NGFR Protein, Fc Tag (NGR-H5254) is expressed from human 293 cells (HEK293). It contains AA Lys 29 - Asn 250 (Accession # P08138-1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Lys 29 - Asn 250.
Conjugate: Unconjugated.
Molecular Weight: 50.0 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.0 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
