Human Neurogranin Protein, His Tag | NEN-H5144-1mg

Human Neurogranin Protein, His Tag | NEN-H5144-1mg| Gentaur Distribution US, UK & Europe

Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain,  particularly in dendritic spines,  and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin,  binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.

Source: Human Neurogranin, His Tag (NEN-H5144) is expressed from E. coli cells. It contains AA Met 1 - Asp 78 (Accession # Q92686).

Format: Powder.

Tag: N-10×His.

Expression System: E. coli.

Expression Region: Met 1 - Asp 78.

Conjugate: Unconjugated.

Molecular Weight: 9.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 9.5 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).

Purity: 95%.

Buffer: 20 mM Tris, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT