Human Mucin-1 / MUC-1 (24-380) Protein, His Tag (MALS verified) | MU1-H52H7-100ug

Human Mucin-1 / MUC-1 (24-380) Protein, His Tag (MALS verified) | MU1-H52H7-100ug| Gentaur Distribution US, UK & Europe

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Source: Human Mucin-1 (24-380) Protein, His Tag (MU1-H52H7) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Ser 380 (Accession # P15941-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ser 24 - Ser 380.

Conjugate: Unconjugated.

Molecular Weight: 35.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.6 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT