Human Mucin-1 / MUC-1 (24-380) Protein, Fc Tag | MU1-H5254-1mg

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SKU:
716-MU1-H5254-1mg
Availability:
IN STOCK
Weight:
1.20 KGS
€3,184.00
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Description

Human Mucin-1 / MUC-1 (24-380) Protein, Fc Tag | MU1-H5254-1mg| Gentaur Distribution US, UK & Europe

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Source: Human Mucin-1 (24-380), Fc Tag (MU1-H5254) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Ser 380 (Accession # P15941-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Ser 24 - Ser 380.

Conjugate: Unconjugated.

Molecular Weight: 60.2 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.2 kDa. The protein migrates as 70 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT

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Additional Information

Size:
1 mg
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