Description
Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag | MU1-H5153-1mg| Gentaur Distribution US, UK & Europe
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
Source: Human Mucin-1 (116-173), Fc Tag (MU1-H5153) is expressed from E. coli cells. It contains AA Ser 116 - Gly 173 (Accession # P15941-8).
Format: Powder.
Tag: C-Fc.
Expression System: E. coli.
Expression Region: Ser 116 - Gly 173.
Conjugate: Unconjugated.
Molecular Weight: 32.7 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.7 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
