Human Mucin-1 / MUC-1 (1098-1158) Protein, Mouse IgG2a Fc Tag | MU1-H5259-1mg

Human Mucin-1 / MUC-1 (1098-1158) Protein, Mouse IgG2a Fc Tag | MU1-H5259-1mg| Gentaur Distribution US, UK & Europe

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Source: Human Mucin-1 (1098-1158), Mouse IgG2a Fc Tag (MU1-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 1098 - Gly 1158 (Accession # P15941-1).

Format: Powder.

Tag: C-mFc (mIgG2a).

Expression System: HEK293.

Expression Region: Ser 1098 - Gly 1158.

Conjugate: Unconjugated.

Molecular Weight: 33.4 kDa.

Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 33.4 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT