Description
Human/Mouse alpha 1 beta 1 (ITGA1&ITGB1) Protein, His Tag&Tag Free (MALS verified) | IN1-H52W9-1mg| Gentaur Distribution US, UK & Europe
Integrin alpha-1/beta-1 is a receptor for laminin and collagen. The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.
Source: Human/Mouse ITGA1&ITGB1 Protein, His Tag&Tag Free (IN1-H52W9) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro1141 & Gln 21 - Asp 728 (Accession # P56199-1 & P09055-1).
Format: Powder.
Tag: C-10×His | Native.
Expression System: HEK293.
Expression Region: Phe 29 - Pro1141 & Gln 21 - Asp 728.
Conjugate: Unconjugated.
Molecular Weight: 130.0 kDa & 83.5 kDa.
Characteristics: Human/Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 130.0 kDa & 83.5 kDa. The protein migrates as 100-115 kDa and >180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50mM Tris, 150mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
