Description
Human MIP4(CCL18) | 90221-B | Gentaur US, UK & Europe Disrtribition
Category: Cytokine
Application: N/A
Background: CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38–, mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma.
Description: Recombinant CCL18 is a disulfide-linked homodimeric protein consisting of 70 amino acid residues and migrates as an approximately 16 kDa protein under non-reducing conditions and 8 kDa under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human MIP-4 mature chain was expressed in E. coli.
Product Type: Protein
Shippement Condition: gel packs or dry ice
