Description
Human Midkine / Mdk Protein, premium grade | MIE-H5117-20ug| Gentaur Distribution US, UK & Europe
Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair.
Source: Human Midkine Protein, premium grade (MIE-H5117) is expressed from E. coli cells. It contains AA Val 21 - Asp 143 (Accession # P21741-1).
Format: Powder.
Tag: Native.
Expression System: E. coli.
Expression Region: Val 21 - Asp 143.
Conjugate: Unconjugated.
Molecular Weight: 13.6 kDa.
Characteristics: This protein carries no "tag". The protein has a calculated MW of 13.6 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
