Description
Human Mesothelin / MSLN (391-598) Protein, Fc Tag (MALS verified) | MSN-H5267-1mg| Gentaur Distribution US, UK & Europe
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
Source: Human Mesothelin (391-598), Fc Tag (MSN-H5267) is expressed from human 293 cells (HEK293). It contains AA Ser 391 - Ser 598 (Accession # AAH09272.1).
Format: Powder.
Tag: N-Fc.
Expression System: HEK293.
Expression Region: Ser 391 - Ser 598.
Conjugate: Unconjugated.
Molecular Weight: 49.6 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 49.6 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
