Description
Human LILRB3 / CD85a / ILT5 Protein, Fc Tag (MALS verified) | CDA-H5250-1mg| Gentaur Distribution US, UK & Europe
Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3, ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
Source: Human LILRB3, Fc Tag (CDA-H5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R) ).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Gly 24 - Glu 443.
Conjugate: Unconjugated.
Molecular Weight: 72.8 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.8 kDa. The protein migrates as 90-115 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
