Human LIGHT / TNFSF14 Protein, Mouse IgG2a Fc Tag, low endotoxin | LIT-H5256-100ug

Human LIGHT / TNFSF14 Protein, Mouse IgG2a Fc Tag, low endotoxin | LIT-H5256-100ug| Gentaur Distribution US, UK & Europe

Tumor necrosis factor ligand superfamily member 14 (LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.

Source: Human LIGHT, Mouse IgG2a Fc Tag, low endotoxin (LIT-H5256) is expressed from human 293 cells (HEK293). It contains AA Asp 74 - Val 240 (Accession # O43557-1).

Format: Powder.

Tag: N-mFc (mIgG2a).

Expression System: HEK293.

Expression Region: Asp 74 - Val 240.

Conjugate: Unconjugated.

Molecular Weight: 45.1 kDa.

Characteristics: This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: Tris with Glycine,  Arginine and NaCl,  pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT